Abstract for non-specialists. This theory proposes that biological aging is driven by the thermodynamic transition of proteins from high-energy states to a rigid, structural minimum. Newly synthesized proteins possess the significant potential energy and flexibility required to perform essential cellular functions. However, as these proteins operate, they transfer their energy...
Many researchers—and non-researchers alike—are daunted by the sheer number of active molecular factors in biology, and in the molecular biology of aging in particular. Consequently, a rather popular view of aging holds that it is an intractable problem due to the multidimensional, multifactorial nature of the observed phenomenon. The aim...
There is no need to treat every individual disease associated with aging. Curing just one is sufficient. The underlying molecular mechanism is identical for every disease. If a substance—or a combination of substances—exists that is capable of fully restoring the function of aged tissue, then that substance (or combination) will...