The fight against aging is not only a medical project. We need first to understand what we are trying to measure, explain, and repair.
Geroscience is where we examine the biological foundations: what aging is, how damage becomes dysfunction, why resilience collapses, which mechanisms are causal, which are only correlated, and how decline can be slowed, reversed, or made irrelevant.
Here we ask the hard questions directly:
No place for vague healthspan language, biomarker theater, or comforting simplifications. Clear thinking about mechanisms, function, causality, repair, translation, clinical endpoints, and human survival.
Here is the place for the war against biological decay.
May your models stay sharp.
If you are looking for an idea on what to write about - here is the list of the questions, that stayed open during the previous discussions:
- Whether the malleability and plasticity of lifespan in some animals proves the potential malleability of lifespan in humans.
- Why can eusocial species change the speed of aging there and back depending on the reproductive role?